Directory

Image of Alexander Katsov
Alexander Katsov Jane Coffin Childs - HHMI Fellow

Rockefeller University

Appointed in 2010

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Image of Jon R. Katze
Jon R. Katze Jane Coffin Childs Fellow

Yale University

Appointed in 1966

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Image of Stephen J. Kaufman
Stephen J. Kaufman Jane Coffin Childs Fellow

Massachusetts Institute of Technology

Appointed in 1971

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Image of Lawrence M. Kauvar
Lawrence M. Kauvar Jane Coffin Childs Fellow

California Institute of Technology

Appointed in 1978

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Image of Justus Kebschull
Justus Kebschull Jane Coffin Childs Fellow

Stanford University

Appointed in 2018

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Brain circuits and the neuronal cell types that form them are not static over evolutionary time. Rather, they cause and reflect the changing repertoire of animal behavior. How circuits and cell types change from their ancestral state to support novel behaviors during evolution, therefore, gives us important clues as to their current function. In my project, I will investigate the interaction between the cerebellum and the rest of the brain from this evolutionary angle by studying the progressive expansion and elaboration of the deep cerebellar nuclei, the output pathway of the cerebellum. I will profile transcriptional and protectional cell types of the DCN across species to probe changes in the DCN over deep evolutionary time. I will then integrate this dataset with developmental trajectories of the identified cell types in mouse, to provide mechanistic insight into how brain regions specialize on the level of single cells and circuit wiring to support new functions over the course of evolution.

Image of James. L. Keck
James. L. Keck Jane Coffin Childs Fellow

Harvard University

Appointed in 1997

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Image of James J. Keirns
James J. Keirns Jane Coffin Childs Fellow

Yale University

Appointed in 1972

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Image of Gregory Kellogg
Gregory Kellogg Jane Coffin Childs Fellow

Harvard University Medical School

Appointed in 1993

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Image of C. Lindley Kemp
C. Lindley Kemp Jane Coffin Childs Fellow

Universite de Geneve, Switzerland

Appointed in 1963

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Image of Jon A. Kenniston
Jon A. Kenniston Jane Coffin Childs Fellow

University of Pennsylvania

Appointed in 2006

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Image of Joan L. L. Kent
Joan L. L. Kent Jane Coffin Childs Fellow

Albert Einstein College of Medicine

Appointed in 1963

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Image of Kenyon J. Kenyon
Kenyon J. Kenyon Jane Coffin Childs Fellow

MRC Center, University Medical School, England

Appointed in 1981

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Image of Daniel S. Kessler
Daniel S. Kessler Jane Coffin Childs Fellow

Harvard University

Appointed in 1991

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Image of Renat Khaliullin
Renat Khaliullin Jane Coffin Childs Fellow - Ludwig Institute

Ludwig Institute for Cancer Research

Appointed in 2012

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Image of Amy A. Kiger
Amy A. Kiger Jane Coffin Childs Fellow

Harvard University Medical School

Appointed in 2001

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Image of Sunyoung Kim
Sunyoung Kim Jane Coffin Childs Fellow

Whitehead Institute for Biomedical Research

Appointed in 1987

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Image of Hui Sun Kim
Hui Sun Kim Jane Coffin Childs Fellow

University of California, Berkeley

Appointed in 1999

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Image of Taekyung Kim
Taekyung Kim Jane Coffin Childs Fellow

Boston Children's Hospital

Appointed in 2003

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Image of Seyun Kim
Seyun Kim Jane Coffin Childs Fellow

Johns Hopkins University

Appointed in 2007

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Image of Hyun-Eui Kim
Hyun-Eui Kim Jane Coffin Childs Fellow

Salk Institute for Biological Studies

Appointed in 2008

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In the lab of Andrew Dillin, I study the mechanism of proteotoxicity in age-onset neurodegenerative diseases such as Alzheimer¬ís and Huntington¬ís. To better understand how protein homeostasis plays a role in these diseases, I use animal model systems ¬ó such as c. elegans and mice ¬ó that express toxic proteins including the amyloid beta peptide (Alzheimer’s) or poly-glutamate protein (Huntington’s).

I was born in Seoul, Korea. My desire to become a  good scientist outweighed anxiety over separating from my family, so I moved to the U.S, obtaining my PhD in biochemistry at the University of Texas Southwest Medical Center. There, I studied the mechanism of cell death and apoptosis, in particularly in various cancer cells. For my postdoc career, I wanted to try new systems to learn more of biology and use my biochemistry expertise. I chose a genetics lab where I can work with live animals and develop a better understanding of pathology in animal model systems, rather than just in groups of cells. I am hopeful that my basic science findings can turn into therapeutic tools. Outside of work, I play piano and paint, and enjoy walking my little dog on the beautiful San Diego beach.

Image of Judith E. Kimble
Judith E. Kimble Jane Coffin Childs Fellow

MRC Center, University Medical School, England

Appointed in 1978

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Image of Bruce E. Kimmel
Bruce E. Kimmel Jane Coffin Childs Fellow

University of California, San Francisco

Appointed in 1991

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Image of Jonathan King
Jonathan King Jane Coffin Childs Fellow

MRC Center, University Medical School, England /
Purdue University

Appointed in 1968

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Image of Robert E. Kingston
Robert E. Kingston Jane Coffin Childs Fellow

Massachusetts Institute of Technology

Appointed in 1982

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Image of Jack F. Kirsch
Jack F. Kirsch Jane Coffin Childs Fellow

University of California, Berkeley /
Brandeis University

Appointed in 1961

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Image of Jan K. Kitajewski
Jan K. Kitajewski Jane Coffin Childs Fellow

University of California, San Francisco

Appointed in 1987

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Image of Matthew Klassen
Matthew Klassen Jane Coffin Childs - HHMI Fellow

University of California, San Francisco

Appointed in 2010

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Image of Robert J. Klebe
Robert J. Klebe Jane Coffin Childs Fellow

Salk Institute for Biological Studies

Appointed in 1971

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Image of George Klein
George Klein Jane Coffin Childs Fellow

Karolinska Institutet, Sweden

Appointed in 1962

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Image of Juli D. Klemm
Juli D. Klemm Jane Coffin Childs Fellow

Stanford University

Appointed in 1996

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Image of Rolf F. Kletzien
Rolf F. Kletzien Jane Coffin Childs Fellow

Sidney Farber Cancer Center

Appointed in 1975

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Image of Steven A. Kliewer
Steven A. Kliewer Jane Coffin Childs Fellow

Salk Institute for Biological Studies

Appointed in 1990

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Image of Lisa S, Klig
Lisa S, Klig Jane Coffin Childs Fellow

Stanford University

Appointed in 1984

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Image of Apostolos Klinakis
Apostolos Klinakis Jane Coffin Childs Fellow

Columbia University

Appointed in 2003

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Image of David M. Knipe
David M. Knipe Jane Coffin Childs Fellow

University of Chicago

Appointed in 1976

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Image of Paul S. Knoepfler
Paul S. Knoepfler Jane Coffin Childs Fellow

Fred Hutchinson Cancer Center

Appointed in 1998

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Image of Bruce D. Koch
Bruce D. Koch Jane Coffin Childs Fellow

University of California, Berkeley

Appointed in 1986

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Image of Thomas J. Kodadek
Thomas J. Kodadek Jane Coffin Childs Fellow

University of California, San Francisco

Appointed in 1985

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Image of Mina Kojima
Mina Kojima Jane Coffin Childs Fellow

Yale University

Appointed in 2019

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Image of Prasanna R. Kolatkar
Prasanna R. Kolatkar Jane Coffin Childs Fellow

Purdue University

Appointed in 1992

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Image of Anthony Koleske
Anthony Koleske Jane Coffin Childs Fellow

Whitehead Institute /
Massachusetts Institute of Technology

Appointed in 1994

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Image of Suzanne F. Komili
Suzanne F. Komili Jane Coffin Childs - HHMI Fellow

University of California, San Francisco

Appointed in 2009

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I am studying genetic determinants of non-genetic variability, or ¬noise,¬î in gene expression using the yeast Saccharomyces cerevisiae.

I started college fully intending to become a physician. However, an excellent first-year interdisciplinary course exposed me to the excitement of research science, and demonstrated the power/utility of using tools from one discipline to study problems in another. I pursued a degree in physics, with the intention of applying the quantitative tools and techniques that I had learned to study biology.

My graduate studies were supervised by both Pam Silver, a molecular and cellular biologist, and Fritz Roth, a statistician and computational biologist. Their joint tutelage allowed me not only to learn fundamental molecular biology and genomics, but also how to analyze data I generated in high-throughput and computational studies. My post-doctoral research on noise in gene expression provides another opportunity to apply mathematical and computational techniques to high-throughput datasets that I am collecting myself. I hope that these studies will provide new insight into problems as fundamental.

Image of Dorethea Kominos
Dorethea Kominos Jane Coffin Childs Fellow

Rockefeller University

Appointed in 1992

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Image of Magda Maria M. Konarska
Magda Maria M. Konarska Jane Coffin Childs Fellow

Massachusetts Institute of Technology

Appointed in 1984

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Image of Erich B. Konrad
Erich B. Konrad Jane Coffin Childs Fellow

Stanford University

Appointed in 1971

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Image of Hyeon-Sook Koo
Hyeon-Sook Koo Jane Coffin Childs Fellow

Johns Hopkins University

Appointed in 1988

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Image of Raphael Kopan
Raphael Kopan Jane Coffin Childs Fellow

Fred Hutchinson Cancer Center

Appointed in 1990

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Image of Casey Kopczynski
Casey Kopczynski Jane Coffin Childs Fellow

University of California, Berkeley

Appointed in 1991

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Image of Alexei M. Korennykh
Alexei M. Korennykh Jane Coffin Childs Fellow

University of California, San Francisco

Appointed in 2007

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Image of Stephen T. Kosak
Stephen T. Kosak Jane Coffin Childs Fellow

Fred Hutchinson Cancer Center

Appointed in 2002

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Image of Michael L. Kotewicz
Michael L. Kotewicz Jane Coffin Childs Fellow

Harvard University

Appointed in 1978

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